I finally joined the ranks of those who’ve installed Visual Studio 2012 this week. The default Light color scheme is way too bright. The Dark color scheme is better, but the grays aren’t differentiated enough (just like the Microsoft Blend UI). Thankfully, some wonderful soul compiled this blog post, which details the changes necessary to save your eyes from the horrible default themes.
Following steps 1 and 2 will be enough, but you can go even further if you want the Visual Studio 2010 icons back in addition to the color scheme.